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Full text (ua) Mathematical analysis of the functional properties of the murine bone marrow in the process of long external gamma-irradiation and after its termination
R. V. Boiko, D. I. B³lko, I. Z. Russu, N. M. B³lko*Abstract: Mathematical model was applied using the experimental results of prolonged round-the-clock γ-irradiation action with the dose rate of 0.25 and 0.5 Gy/day on the alterations in colony-forming units (CFU) number in murine bone marrow, as well as experimental data, concerning the process of CFU recovery after the termination of 30- and 100-day irradiation. Mathematical parameters were determined which characterize the hematopoiesis reaction to the CFU loss as a result of prolonged ionizing radiation action with different dose rates, as well as the process of CFU number recovery after irradiation termination.
Keywords: ionizing radiation, bone marrow, functional properties, mathematical modeling.
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