Nuclear Physics and Atomic Energy


Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
  Periodicity: 4 times per year

  Open access peer reviewed journal


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Nucl. Phys. At. Energy 2016, volume 17, issue 4, pages 388-393.
Section: Radiobiology and Radioecology.
Received: 22.06.2016; Accepted: 19.10.2016; Published online: 10.04.2017.
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Dynamics of free radicals processes in rat blood with partially blocked thyroid gland by stable iodine

Yu. P. Grynevych, A. I. Lypska, I. P. Drozd*, S. V. Teletska

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address: radiobiology@kinr.kiev.ua

Abstract: Free radicals' processes in blood of male rats Wistar, induced by 22 chemiluminescence for single oral ingestion of 131 in organism at 65.9 kBq per animal in conditions of partially blocked thyroid gland with 127I, were studied. The introduction of radioactive iodine, as well as partial blocking of thyroid gland by iodine, do not influence significantly on changing of prooxidant-antioxidant homeostasis and oxidative correlation lipid peroxidation in blood for chemiluminescence reaction (sum light emission, the final intensity of the light emission, maximum intensity of the first flash light emission, velocity formation of free radicals, time to reach maximum values intensity of the first flash light emission). There were no significant changes in catalase activities in the experimental rat blood from those in the control group rats.

Keywords: radioactive iodine, stable iodine, internal exposure, free radicals processes, chemiluminescence, blood, Wistar rats.

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