Nuclear Physics and Atomic Energy

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Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
  Periodicity: 4 times per year

  Open access peer reviewed journal

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Nucl. Phys. At. Energy 2018, volume 19, issue 3, pages 265-269.
Section: Radiobiology and Radioecology.
Received: 05.04.2018; Accepted: 11.10.2018; Published online: 04.12.2018.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2018.03.265

Comparative mathematical analysis of the colony-forming ability of bone marrow of mice irradiated in lethal dose with high and low dose rate

R. V. Boiko, D. I. B³lko, I. Z. Russu, N. M. B³lko*

National University of “Kyiv-Mohyla Academy”, Kyiv, Ukraine

*Corresponding author. E-mail address: nbilko@ukma.kiev.ua

Abstract: Using (1) original mathematical model, (2) new scheme of hematopoiesis and experimental results of γ-irradiation influence in the dose of 8 Gy with 5 and 0.0028 Gy/min dose rate on the number of colony-forming units (CFU) of bone marrow (BM), as well as (3) experimental data concerning the reparation processes of BM CFU, obtained from the scientific publications, we determine parameters characterizing the reaction of hematopoietic system on the different stages of reparation processes of BM CFU number after the termination of ionizing radiation action.

Keywords: ionizing radiation, lethal dose, bone marrow, functional properties, mathematical modeling.

References:

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2. R.V. Boiko et al. Mathematical analysis of functional properties alterations of mice bone marrow during protracted external irradiation with different dose rate intensity. Yaderna Fizyka ta Energetyka (Nucl. Phys. At. Energy) 16(4) (2015) 389. (Ukr) https://doi.org/10.15407/jnpae2015.04.389

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