Ядерна фізика та енергетика Nuclear Physics and Atomic Energy   ISSN: 1818-331X (Print), 2074-0565 (Online)   Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine   Languages: Ukrainian, English, Russian   Periodicity: 4 times per year   Open access peer reviewed journal

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Yu. P. Grynevych^1,*, А. І. Lypska¹, І. P. Drozd¹, N. O. Druzhyna², S. V. Teletska¹, L. I. Makovetska<sup>2

1</sup> Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine
² R. Е. Kavetsky Institute of Experimental Pathology and Oncology, National Academy of Sciences of Ukraine, Kyiv, Ukraine

^*Corresponding author. E-mail address: radiobiology@kinr.kiev.ua

Abstract: The dynamics of free radical processes in the blood of mature male Wistar rats were studied by chemiluminescence after a single injection of ¹³¹I (114.8 kBq) and ⁹⁰Sr + ⁹⁰Y (113.9 kBq). Changes in the course of the physicochemical regulation of the prooxidant-oxidant ratio in the early stages of the influence of these radionuclides, which were manifested in the imbalance between the level of intensity of the formation of free radicals and the efficiency of their elimination by the antioxidant system, were revealed. The differences in the dynamics of free radical processes in the blood of rats are obviously due to the nuclear-physical and biological characteristics of radionuclides of various tropics.

Keywords: сhemiluminescence, free radical processes, ¹³¹I, ⁹⁰Sr + ⁹⁰Y, blood, Wistar line male rats.

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