Nuclear Physics and Atomic Energy


Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
  Periodicity: 4 times per year

  Open access peer reviewed journal


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Nucl. Phys. At. Energy 2020, volume 21, issue 2, pages 166-171.
Section: Radiobiology and Radioecology.
Received: 17.10.2019; Accepted: 19.03.2020; Published online: 3.09.2020.
PDF Full text (en)
https://doi.org/10.15407/jnpae2020.02.166

Simulation of conditions for external and internal exposure of human blood to low doses of 137Cs radionuclide in vitro to study its genotoxicity

L. K. Bezdrobna*, M. V. Strilchuk, V. A. Kurochkina, V. I. Fedorchenko, I. A. Khomych, T. V. Tsyganok

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address: lbezdrob@ukr.net

Abstract: Proposed are the models for external exposure to and contamination with 137Cs (imitation of internal exposure) of human blood samples in vitro in doses up to 0.53 Gy for 1.75 h. Exposure conditions and experimental devices, as well as models for the calculation of the absorbed doses under external irradiation and estimation of the activity of the radioisotope needed to obtain the desired absorbed dose under internal exposure of blood cells, are presented. The created experimental models allow conduction of comparative in vitro studies of the 137Cs genotoxicity at external and internal exposure of human blood.

Keywords: 137Cs, in vitro radiation simulation, external exposure, internal exposure, human blood, absorbed dose calculation.

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