Nuclear Physics and Atomic Energy

ядерна ф≥зика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English
  Periodicity: 4 times per year

  Open access peer reviewed journal

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Nucl. Phys. At. Energy 2021, volume 22, issue 3, pages 300-307.
Section: Radiobiology and Radioecology.
Received: 17.11.2021; Accepted: 22.12.2021; Published online: 22.02.2022.
PDF Full text (ua)

Chromosome aberrations in human lymphocytes due to external and/or internal irradiation of blood samples by 137Cs in model experiments in vitro

V. A. Kurochkina*, L. K. Bezdrobna, T. V. Tsyhanok, M. V. Strilchuk, I. A. Maliuk

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address:

Abstract: The linear dependence of the yield of unstable chromosomal aberrations in human lymphocytes on the dose of prolonged external and/or internal irradiation of peripheral blood samples by 137Cs in the dose range of 0.09 - 0.54 Gy in vitro is presented. The higher cytogenetic efficiency of internal 137Cs irradiation is shown in comparison with external. It is shown that the cytogenetic efficiency of 137Cs in blood contamination is caused by influence on cells not only in the mitotic rest phase but during proliferation, within intracellular radioactivity through their cultivation. It is proposed to use the presented dose dependences of the yield of chromosomal aberrations in lymphocytes in vitro for human biological dosimetry during radiation accidents associated with prolonged external exposure or 137Cs incorporation to the body as a supplement to the results of physical dosimetry.

Keywords: 137Cs external irradiation, internal irradiation, human blood lymphocytes, chromosomal aberrations, biological dosimetry.


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