Nuclear Physics and Atomic Energy

ядерна ф≥зика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English
  Periodicity: 4 times per year

  Open access peer reviewed journal


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Nucl. Phys. At. Energy 2021, volume 22, issue 3, pages 312-317.
Section: Engineering and Methods of Experiment.
Received: 17.11.2020; Accepted: 22.12.2021; Published online: 22.02.2022.
PDF Full text (ua)
https://doi.org/10.15407/jnpae2021.03.312

Inductive hyperthermia planning for patients with breast cancer metastasis to lymph nodes

O. I. Mokhonko1, V. E. Orel2,3,*, I. I. Smolanka (Sr.)2, L. A. Syvak2, A. D. Loboda2, I. V. Dosenko2, A. O. Lyashenko2, I. I. Smolanka (Jr.)2, O. Yu. Rykhalskyi2, V. B. Orel2,3, O. I. Dasyukevich2, T. Ye. Tarasenko2, S. I. Vovyanko3

1 Taras Shevchenko National University of Kyiv, Kyiv, Ukraine
2 National Cancer Institute, Kyiv, Ukraine
3 National Technical University of Ukraine "Igor Sikorsky Kyiv Polytechnic Institute", Kyiv, Ukraine


*Corresponding author. E-mail address: valeriiorel@gmail.com

Abstract: Inductive hyperthermia treatment plans were built using Comsol Multiphysics software for patients with breast cancer metastasis to lymph nodes. To assess the influence of electromagnetic irradiation on temperature increase in metastatic lymph nodes, treatment plans were based on moderate hyperthermia parameters (< 42 °C). The proposed technology can be used to provide a more personalized approach to treatment planning for patients with locally advanced breast cancer receiving combination therapy which involves neoadjuvant chemotherapy and expand eligibility for organ-preserving surgery.

Keywords: inductive hyperthermia, breast cancer, metastasis, lymph nodes, computer planning.

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