Nuclear Physics and Atomic Energy

ядерна ф≥зика та енергетика
Nuclear Physics and Atomic Energy

  ISSN: 1818-331X (Print), 2074-0565 (Online)
  Publisher: Institute for Nuclear Research of the National Academy of Sciences of Ukraine
  Languages: Ukrainian, English, Russian
  Periodicity: 4 times per year

  Open access peer reviewed journal


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Nucl. Phys. At. Energy 2015, volume 16, issue 2, pages 157-163.
Section: Radiobiology and Radioecology.
Received: 02.06.2015; Accepted: 11.06.2015; Published online: 20.07.2015.
PDF Full Text (ua)
https://doi.org/10.15407/jnpae2015.02.157

Simulation of 131I emergency emission. Processes of dose formation

I. P. Drozd*, O. A. Sova, A. I. Lypska

Institute for Nuclear Research, National Academy of Sciences of Ukraine, Kyiv, Ukraine

*Corresponding author. E-mail address: radiobilogy@kinr.kiev.ua

Abstract: Kinetics of 131I and dose formation in tissues and organs of laboratory Wistar rats in a simulation of long entry of the isotope were studied. The function of weight of the thyroid gland changes due to accumulation of absorbed dose in the body was optimized. Maximum activity of the initial ingestion of the isotope in the body, above which the thyroid tissue loses its ability to retain iodine was substantiated. Residual thyroid tissue mass after radiation damage was estimated. Features of the processes of dose formation in other tissues and organs were described.

Keywords: isotope 131I, thyroid gland, accumulation of iodine, dose formation, athyreosis.

References:

1. I.P. Drozd, A.I. Lyps'ka, L.K. Bezdrobna et al. Investigation of 131I kinetics in the rats organism after a single intake. Nucl. Phys. At. Energy 13(3) (2012) 283. (Ukr) http://jnpae.kinr.kiev.ua/13.3/Articles_PDF/jnpae-2012-13-0283-Drozd.pdf

2. O.A. Sova, I.P. Drozd. Dose formation and hematologic effects with prolonged internal exposure of rats by isotope 131I. Nucl. Phys. At. Energy 15(4) (2014) 359. (Ukr) http://jnpae.kinr.kiev.ua/15.4/Articles_PDF/jnpae-2014-15-0359-Sova.pdf

3. I.P. Drozd, O.A. Sova, A.I. Lypska. Dynamics of 131I accumulation and formation of doses in organs and tissues of the laboratory rats by prolonged oral intake. Nucl. Phys. At. Energy 16(1) (2015) 60. (Ukr) http://jnpae.kinr.kiev.ua/16.1/Articles_PDF/jnpae-2015-16-0060-Drozd.pdf

4. L.A. Ilyin, Yu. I. Moskalyov (Eds.). Distribution, Kinetics Exchange and Biological Effects of Radioactive Iodine Isotopes: Collection of Papers (Moskva: Medicine, 1970) 240 p. (Rus)